HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → (4Z,7Z,10Z,13Z,16Z,19Z)-N-(Pyridin-4-yl)docosa-4,7,10,13,16,19-hexaenamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Docosahexenoic acid | HCID 175542 | — |
| Product | (4Z,7Z,10Z,13Z,16Z,19Z)-N-(Pyridin-4-yl)docosa-4,7,10,13,16,19-hexaenamide | HCID 59539431 | 91% |
Reaction Steps
Reaction of docosahexaenoic acid (0.10 g, 0.30 mmol) with 4-aminopyridine (0.03 g, 0.30 mmol) was conducted according to the general amide coupling procedure using DCC to obtain the product as a yellow solid (0.11 g, 91%). EIMS m/z: 405 ([M]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08791275B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-d2c987f85cc0431eb99d2e24c827e201 |
| Source note | uspto-grants-2014_07 |