Sodium Hydroxide → Spiro[4.5]deca-6,9-dien-8-one

Participants

Reaction Conditions

Reaction Steps

A 25% sodium hydroxide aqueous solution, 4.8 g, was added to 5.5 g of p-(4-chlorobutyl)phenol and stirred. The mixture was slowly heated under reduced pressure while removing water (until 120° C. at 50 Pa) and subsequently heated to 180-200° C., at which a distillate was collected. There was obtained 2.11 g (yield 47%) of spiro[4.5]deca-6,9-dien-8-one.

Provenance & Evidence