Spiro[4.5]decane-7,9-dione → 9-Isobutyloxyspiro[4.5]dec-8-en-7-one

Participants

Reaction Steps

By following a procedure analogous to that described in Organic Syntheses, Collective Volume 5, p 539, using 81.2 g of spiro[4.5]decane-7,9-dione instead of dihydroresorcinol and isobutyl alcohol instead of ethyl alcohol, a corresponding isobutyl enol ether was prepared. It was purified by silica gel chromatography, obtaining 9-isobutyloxyspiro[4.5]dec-8-en-7-one in a yield of 56%.

Provenance & Evidence