HCID 66867027, compound → HCID 68089186, compound

Participants

Reaction Steps

To 5% w/w Pd/C (5 mg) was added a solution of 4-[1-cyclopropyl-methylidene]-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione (28 mg, 0.09 mmol) in MeOH (10 ml). The reaction was stirred under an atmosphere of H2 (1.5 bar) for 1.5 hours, filtered through a pad of celite and washed through with MeOH (20 ml). The solvent was removed under reduced pressure to give the crude product (20 mg) which was purified by mass-directed HPLC to give the desired product (5 mg).

Provenance & Evidence