HCID 66867987, compound → HCID 66867962, compound

Participants

Reaction Steps

To a mixture of 4-[1-(4-Methoxy-cyclohexyl)-meth-(E)-ylidene]-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione (150 mg, 0.44 mmol) and ethanol (3.5 ml) is added 5% palladium on carbon (30 mg) and the resulting mixture hydrogenated at 3 bar pressure for 3 hours. The reaction mixture is then filtered through celite and the filtrate concentrated under reduced pressure to give 4-(4-Methoxy-cyclohexylmethyl)-2-(2,4,6-trimethyl-phenyl)-cyclopentane-1,3-dione as a pale yellow solid (142 mg).

Provenance & Evidence