Chlorine → HCID 20443860, compound

HRID 1632183Notes

Reaction equation

HRID 1632183 reaction equation
[CH:1]1[C:2]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[CH2:9][O:8][C:3]=2[NH:4][C:5](=[O:7])[CH:6]=1.[Cl:16]Cl>C(O)(=O)C>[Cl:16][C:6]1[C:5](=[O:7])[NH:4][C:3]2[O:8][CH2:9][C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[C:2]=2[CH:1]=1

Participants

4

Reactant 2

HCID 24526ChlorineHCID 20443853HCID 20443853, compound

Product 1

HCID 20443860HCID 20443860, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Add 19.7 gm of 4,6-dihydro-3H[2]benzopyrano-[3,4-b]pyridin-3-one to 300 ml of acetic acid. Bubble chlorine into the reaction solution for 4 hours at 100°. Cool the system and collect the product as a precipitate. Dissolve the solid into water and neutralize the solution with 1N NaOH. Extract the product with chloroform. Dry the chloroform over anhydrous magnesium sulfate and filter the solution. Remove the solvent by stripping to give the title compound.

Workup

  1. temperatureCool the system
  2. customcollect the product as a precipitate
  3. dissolutionDissolve the solid into water
  4. extractionExtract the product with chloroform
  5. dry with materialDry the chloroform over anhydrous magnesium sulfate
  6. filtrationfilter the solution
  7. customRemove the solvent

Sources & evidence

ORD record
ord-f62061da7536439286a8a2ceb660b2fe
Source dataset
uspto-grants-1984_10
Patent number
US04474786

Reaction notes

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