反应详情

A mixture of 40 g of activated manganese dioxide and a solution of 5.0 g (20.6 mmole) of the product of Example 24 in 500 ml of chloroform was vigorously stirred for 3 hours and was then filtered through celite. The filtrate was evaporated to dryness and the residue was triturated with ether to obtain 3.9 g (80% yield) of 4,5-dihydro-5-ethyl-4-oxopyrrolo-[1,2-a]-quinoxaline-2-carboxaldehyde in the form of colorless needles melting at 252°-255° C.

1. filtrationwas then filtered through celite
2. customThe filtrate was evaporated to dryness
3. customthe residue was triturated with ether