HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetramethylpyrazine → 2-(2-Hydroxy-2-p-methoxyphenylethyl)-3,5,6-trimethylpyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetramethylpyrazine | HCID 14296 | — |
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Product | 2-(2-Hydroxy-2-p-methoxyphenylethyl)-3,5,6-trimethylpyrazine | HCID 585940 | 52.1% |
Reaction Steps
The reaction of 13.6 grams (0.1 mole) of tetramethylpyrazine with 13.6 grams (0.1 mole) of p-anisaldehyde was conducted in the manner described in Example II. Crystallization of the recovered crude product from ether yielded 14.2 grams (52%) of white crystals, m.p. 97°-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04474819 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-b1bfb7f70bb54ec1b8d055cf33a20df9 |
| Source note | uspto-grants-1984_10 |