HRID1632391

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID176

Acetic Acid

C2H4O2

结构：CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)O

HCID131713841

未命名化合物

PRODUCTS

生成物

结构：CC[C@H](C)[C@H](NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)O

HCID131713842

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

0.50 Gram of Z-Leu-Ile-Leu-Leu-Ala-Gln-OH was dissolved in 50 ml of methanol and 10 ml of 10%-acetic acid, and the mixture was catalytically reduced by using palladium as a catalyst to obtain H-Leu-Ile-Leu-Leu-Ala-Gln-OH. Hereinafter, this product is referred to as [Peptide A].

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-136aa19ef49644d6ba788cee47b75ab5
来源数据集: uspto-grants-1984_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04474754
来源说明: uspto-grants-1984_10

反应 SMILES

[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:7]([NH:9][C@H:10]([C:15]([NH:17][C@H:18]([C:23]([NH:25][C@H:26]([C:31]([NH:33][C@H:34]([C:36]([NH:38][C@H:39]([C:45]([OH:47])=[O:46])[CH2:40][CH2:41][C:42](=[O:44])[NH2:43])=[O:37])[CH3:35])=[O:32])[CH2:27][CH:28]([CH3:30])[CH3:29])=[O:24])[CH2:19][CH:20]([CH3:22])[CH3:21])=[O:16])[C@H:11]([CH2:13][CH3:14])[CH3:12])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].C(O)(=O)C>CO.[Pd]>[NH2:1][C@H:2]([C:7]([NH:9][C@H:10]([C:15]([NH:17][C@H:18]([C:23]([NH:25][C@H:26]([C:31]([NH:33][C@H:34]([C:36]([NH:38][C@H:39]([C:45]([OH:47])=[O:46])[CH2:40][CH2:41][C:42](=[O:44])[NH2:43])=[O:37])[CH3:35])=[O:32])[CH2:27][CH:28]([CH3:29])[CH3:30])=[O:24])[CH2:19][CH:20]([CH3:21])[CH3:22])=[O:16])[C@H:11]([CH2:13][CH3:14])[CH3:12])=[O:8])[CH2:3][CH:4]([CH3:5])[CH3:6]