Acetic Acid → HCID 178427567, compound

HRID 1632429Notes

Reaction equation

HRID 1632429 reaction equation
[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:20]([NH:22][C@H:23]([C:26]([NH:28][C@H:29]([C:32]([OH:34])=[O:33])[CH2:30][OH:31])=[O:27])[CH2:24][OH:25])=[O:21])[CH2:3][CH2:4][CH2:5][NH:6][C:7](=[NH:19])[NH:8][S:9]([C:12]1[CH:18]=[CH:17][C:15]([CH3:16])=[CH:14][CH:13]=1)(=[O:11])=[O:10].C(O)(=O)C>CO.[Pd]>[NH2:1][C@H:2]([C:20]([NH:22][C@H:23]([C:26]([NH:28][C@H:29]([C:32]([OH:34])=[O:33])[CH2:30][OH:31])=[O:27])[CH2:24][OH:25])=[O:21])[CH2:3][CH2:4][CH2:5][NH:6][C:7](=[NH:19])[NH:8][S:9]([C:12]1[CH:13]=[CH:14][C:15]([CH3:16])=[CH:17][CH:18]=1)(=[O:10])=[O:11]

Participants

5

Reactant 2

HCID 176Acetic AcidHCID 178427580HCID 178427580, compound

Product 1

HCID 178427567HCID 178427567, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

1.35 Grams of Z-Arg(Tos)-Ser-Ser-OH was dissolved in 50 ml of methanol and 10 ml of 10%-acetic acid, and the solution was subjected to catalytical reduction in the presence of 500 mg of palladium at 20° C. under an atmospheric pressure to obtain H-Arg(Tos)-Ser-Ser-OH.

Sources & evidence

ORD record
ord-fc75d9cd13064b14a262661de81bbd2e
Source dataset
uspto-grants-1984_10
Patent number
US04474754

Reaction notes

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