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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 163243Generated: October 25, 2026

Tetrahydrofuran → Tert-butyl 4-cyano-4-(cyclopropylmethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/163243

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantBromomethylcyclopropaneHCID 81503—
ReactantTert-butyl 4-cyanopiperidine-1-carboxylateHCID 1514443—
ReactantDiisopropylamideHCID 5062348—
ProductTert-butyl 4-cyano-4-(cyclopropylmethyl)piperidine-1-carboxylateHCID 57425738—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-34e175039db24f238be669c1a73610a3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)