反应详情

温度

25 °C

By the procedure of Example 1, 7.1 g of chlorosulfonyl isocyanate was added to a suspension containing 8.1 g of 2-(1,3,4-oxadiazol-2-yl)phenol [prepared by the procedure of J. Maillard et al., Bull. Soc. Chim. France, 3, 529 (1961)] in 125 ml of dry toluene. The reaction mixture was stirred at 25° C. for 1 hour, then heated at 100° to 110° C. for about 0.5 hour. The resulting suspension containing a viscous oil was cooled to 25° C., filtered, and the filtrate was concentrated in vacuo to yield 8 g of the title compound as a viscous, crude oil. The IR spectrum showed an isocyanate absorption at 2220 cm-1.

1. customprepared by the procedure of J
2. temperatureheated at 100° to 110° C. for about 0.5 hour
3. additionThe resulting suspension containing a viscous oil
4. temperaturewas cooled to 25° C.
5. filtrationfiltered
6. concentrationthe filtrate was concentrated in vacuo