4-Nitro-N-methylphthalimide → Ether phthalimide

HRID 1632542Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1632542
C(OB([O:12][C:13]([CH3:16])(C)C)OC(C)(C)C)(C)(C)C.[OH:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]([C:27]2[CH:32]=[CH:31][C:30]([OH:33])=[CH:29][CH:28]=2)([CH3:26])[CH3:25])=[CH:20][CH:19]=1.[Na:34].[Na].C[N:37]1[C:41](=[O:42])[C:40]2=[CH:43][C:44]([N+]([O-])=O)=[CH:45][CH:46]=[C:39]2[C:38]1=[O:50]>C1(C)C=CC=CC=1>[OH:17][C:18]1[CH:19]=[CH:20][C:21]([C:24]([C:27]2[CH:28]=[CH:29][C:30]([OH:33])=[CH:31][CH:32]=2)([CH3:26])[CH3:25])=[CH:22][CH:23]=1.[Na:34].[Na:34].[CH3:38][CH2:39][O:12][CH2:13][CH3:16].[C:41]1(=[O:42])[NH:37][C:38](=[O:50])[C:39]2=[CH:46][CH:45]=[CH:44][CH:43]=[C:40]12

Komponenten

6

Edukt 3

HCID 923214-Nitro-N-methylphthalimideHCID 289737Tri-tert-butyl borateHCID 66941220disodium bisphenol-A

Produkt 2

HCID 18959638Ether phthalimideAusbeute 77 %HCID 66941220disodium bisphenol-A

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

The anhydrous salt of disodium bisphenol-A was prepared in accordance with the method shown in Takekoshi, U.S. Pat. No. 4,202,993, assigned to the same assignee as the present invention and incorporated herein by reference. There was added under ambient conditions with stirring 50 microliters of tri-t-butylborate to a slurry of 1.5 grams of the anhydrous salt of disodium bisphenol-A and 2.27 grams of N-methyl-4-nitrophthalimide in 8 ml of toluene. The resulting reaction mixture was then heated with stirring to reflux for 30 minutes. There was obtained a 77% yield of an ether phthalimide having the formula, ##STR7## based on reverse phase liquid chromatography using ortho-terphenyl as an internal standard.

Aufarbeitung

  1. additionThere was added under ambient conditions
  2. customThe resulting reaction mixture
  3. temperaturewas then heated
  4. temperatureto reflux for 30 minutes

Quellen und Nachweise

ORD-Eintrag
ord-26d20b4e12ad4e53855a706d43eb50c3
Quelldatensatz
uspto-grants-1984_10
Patentnummer
US04476309

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