HRID1632710

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC[C@H]1CC[C@H](C2CC=C(c3ccc(C4=CCC([C@H]5CC[C@H](CCC)CC5)CC4)cc3)CC2)CC1

HCID178447831

未命名化合物

PRODUCTS

生成物

结构：CCC[C@H]1CC[C@H]([C@H]2CC[C@H](c3ccc([C@H]4CC[C@H]([C@H]5CC[C@H](CCC)CC5)CC4)cc3)CC2)CC1

HCID178448008

未命名化合物

收率 33.1%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID935

Nickel

溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

Raney Ni catalyst (0.5 g) was added to a solution of 1,4-bis[4-(trans-4-propylcyclohexyl)cyclohexen-1-yl]benzene (0.9 g) dissolved in toluene (70 ml), followed by subjecting to catalytic reduction at ordinary temperature under ordinary pressure, tracing the reaction by gas chromatography and stopping the reaction when the raw material disappeared. Since the product was a mixture of cis-form and trans-form substances, it was recrystallized from toluene to obtain an objective product, 1,4-bis[trans-4-(trans-4-propylcyclohexyl)cyclohexyl]benzene (yield: 0.3 g, C-Sm point: room temperature or lower, Sm-I point: 300° C. or higher).

WORKUP

后处理

customthe reaction by gas chromatography
additiona mixture of cis-form and trans-form substances, it
customwas recrystallized from toluene

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-41f17230653e49b2bfbc5240f73e346f
来源数据集: uspto-grants-1984_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04477369
来源说明: uspto-grants-1984_10

反应 SMILES

[CH2:1]([C@H:4]1[CH2:9][CH2:8][C@H:7]([CH:10]2[CH2:15][CH2:14][C:13]([C:16]3[CH:21]=[CH:20][C:19]([C:22]4[CH2:27][CH2:26][CH:25]([C@H:28]5[CH2:33][CH2:32][C@H:31]([CH2:34][CH2:35][CH3:36])[CH2:30][CH2:29]5)[CH2:24][CH:23]=4)=[CH:18][CH:17]=3)=[CH:12][CH2:11]2)[CH2:6][CH2:5]1)[CH2:2][CH3:3]>[Ni].C1(C)C=CC=CC=1>[CH2:1]([C@H:4]1[CH2:5][CH2:6][C@H:7]([C@H:10]2[CH2:11][CH2:12][C@H:13]([C:16]3[CH:21]=[CH:20][C:19]([C@H:22]4[CH2:27][CH2:26][C@H:25]([C@H:28]5[CH2:29][CH2:30][C@H:31]([CH2:34][CH2:35][CH3:36])[CH2:32][CH2:33]5)[CH2:24][CH2:23]4)=[CH:18][CH:17]=3)[CH2:14][CH2:15]2)[CH2:8][CH2:9]1)[CH2:2][CH3:3]