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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1632740Generated: October 25, 2026

Triethylamine → HCID 20442368, compound

https://huagongshe.com/reaction/1632740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantButanoic acid, 4-chloro-4-oxo-, methyl esterHCID 73888—
Reactant5-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamideHCID 12736892—
SolventAcetoneHCID 180—
ProductHCID 20442368HCID 20442368—

Reaction Steps

A solution of 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide (3.19 g; 0.1 mole) in acetone (60 ml) at -10° was treated with triethylamine (1.11 g; 0.011 mole). Then methoxycarbonylpropionyl chloride (1.66 g; 0.011 mole) was added, dropwise, during 5 minutes at -10°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04477466
Source datasetuspto-grants-1984_10
ORD IDord-ace74607f05a4b5db29b180e6955764d
Source noteuspto-grants-1984_10