HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 4-[(2-Sulfamoyl-5-thienyl)sulfonyl]phenyl Acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 5-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamide | HCID 12736892 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-[(2-Sulfamoyl-5-thienyl)sulfonyl]phenyl Acetate | HCID 13390109 | — |
Reaction Steps
A solution of 5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide (3.19 g; 0.01 mole) in acetone (60 ml) at -10° was treated with triethylamine (1.11 g; 0.011 mole). Then acetyl chloride (0.86 g; 0.011 mole) was added, dropwise, during 5 minutes at -10°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04477466 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-6e9e351226344edcaa98445708c6cfa9 |
| Source note | uspto-grants-1984_10 |