Maleic Anhydride → 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-2(3H)-furanone

Participants

Reaction Steps

Following a procedure similar to that described above in part A of this example except that 2,4-bis(6-fluoro-1-benzyl-3-indolyl)-4-oxobutanoic acid prepared by interaction of maleic anhydride and 6-fluoro-1-benzylindole by a procedure similar to that described in Example 3, part A is used in place of 2,4-bis(1-ethyl-2-methyl-3-indolyl)-4-oxobutanoic acid, there is obtained 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-2(3H)-furanone (Formula II: R=C6H5CH2 ; R1 =H; Y=6-F).

Provenance & Evidence