Pyridine → Nitrobenzene

HRID 1632924Notes

Reaction equation

HRID 1632924 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)([O-:3])=[O:2].[N:10]1[CH:15]=CC=CC=1.[C]=O.Cl[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1Cl>>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:19]1([N:10]=[C:15]=[O:2])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

6

Reactant 4

HCID 1049PyridineHCID 72391,2-DichlorobenzeneHCID 7416NitrobenzeneHCID 178418416HCID 178418416, compound

Product 2

HCID 7416NitrobenzeneHCID 7672Phenyl isocyanate

Procedure

1.8 g of this catalyst as well as 10 g of nitrobenzene and 1 g of pyridine are charged into the autoclave used in Example 2 and the volume is made up to a total volume of 100 ml with the addition of ortho-dichlorobenzene. By operating in an identical fashion with Example 2 at 240° C. under 200 bars of carbon monoxide at 20° C., a T.T.G. (overall conversion rate) of nitrobenzene of 100% and a phenylisocyanate selectivity of 62% are obtained.

Sources & evidence

ORD record
ord-f268808d3b0041858d01cf0cc7099bcf
Source dataset
uspto-grants-1984_10
Patent number
US04478757

Reaction notes

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