HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-(3,4,5-Trimethoxycinnamoyl)-4-[1-(ethylaminocarbonyl)ethyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Propenoyl chloride, 3-(3,4,5-trimethoxyphenyl)-, (2E)- | HCID 112094 | — |
| Reactant | N-Ethyl-2-(piperazin-1-yl)propanamide | HCID 13340427 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(3,4,5-Trimethoxycinnamoyl)-4-[1-(ethylaminocarbonyl)ethyl]piperazine | HCID 54340118 | — |
Reaction Steps
17.19 g of 3,4,5-trimethoxycinnamoyl chloride and 6.78 g of triethylamine are added with ice cooling to a solution of 9.54 g of 1-[1-(ethylaminocarbonyl)ethyl]piperazine in 200 ml of chloroform, and the resulting solution is kept standing at room temperature for 1 hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04478838 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-97c364da0c52479d931c09a58d290af7 |
| Source note | uspto-grants-1984_10 |