HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-(3,4,5-Trimethoxycinnamoyl)-4-[1-(propylaminocarbonyl)ethyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Propenoyl chloride, 3-(3,4,5-trimethoxyphenyl)-, (2E)- | HCID 112094 | — |
| Reactant | 1-[1-(Propylaminocarbonyl)ethyl]piperazine | HCID 20441632 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(3,4,5-Trimethoxycinnamoyl)-4-[1-(propylaminocarbonyl)ethyl]piperazine | HCID 54029513 | — |
Reaction Steps
20.00 g of 3,4,5-trimethoxycinnamoyl chloride and 11.77 ml of triethylamine are added with ice cooling to a solution of 12.90 g of 1-[1-(propylaminocarbonyl)ethyl]piperazine in 200 ml of chloroform and stirred at room temperature for one-half an hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04478838 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-dddbea3bf2fb43b2815ce1d68a3ba740 |
| Source note | uspto-grants-1984_10 |