Ethanolamine → HCID 13043496, compound

HRID 1633023Notes

Reaction equation

Cl[C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][OH:18])[C:6]=2[N:7]=1.[OH:26][CH2:27][CH2:28][NH2:29]>>[OH:26][CH2:27][CH2:28][NH:29][C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][OH:18])[C:6]=2[N:7]=1

Participants

Reactant 2

HCID 700Ethanolamine

HCID 13043393HCID 13043393, compound

Product 1

HCID 13043496HCID 13043496, compound

Procedure

This compound was prepared analogous to Example 2 from 2-chloro-8-(5-hydroxypentyl-amino)-4-(1-oxidothiomorpholino)-pyrimido[5,4-d]pyrimidine (melting point: 202°-204° C.) and 2-hydroxyethyl-amine.

Sources & evidence

ORD record: ord-1d57cf61e30e43689ca19efb0791e133
Source dataset: uspto-grants-1984_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04478833

Reaction notes

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