Ethanolamine → HCID 13043500, compound

HRID 1633026Notes

Reaction equation

Cl[C:2]1[N:3]=[C:4]([N:21]2[CH2:26][CH2:25][S:24](=[O:27])[CH2:23][CH2:22]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([N:12]([CH3:20])[CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:6]=2[N:7]=1.[OH:28][CH2:29][CH2:30][NH2:31]>>[OH:28][CH2:29][CH2:30][NH:31][C:2]1[N:3]=[C:4]([N:21]2[CH2:22][CH2:23][S:24](=[O:27])[CH2:25][CH2:26]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([N:12]([CH3:20])[CH2:13][C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)[C:6]=2[N:7]=1

Participants

Reactant 2

HCID 700Ethanolamine

HCID 12817036HCID 12817036, compound

Product 1

HCID 13043500HCID 13043500, compound

Procedure

This compound was prepared analogous to Example 2 from 2-chloro-8-[N-methyl-N-(3-picolyl)-amino]-4-(1-oxidothiomorpholino)-pyrimido[5,4-d]pyrimidine (melting point: 154°-156° C.) and 2-hydroxyethyl-amine.

Sources & evidence

ORD record: ord-8b74c022df0c49cbb0287db5a26e022e
Source dataset: uspto-grants-1984_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04478833

Reaction notes

Loading…