Ethanolamine → HCID 13043515, compound

HRID 1633029Notes

Reaction equation

HRID 1633029 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:25]2[CH2:30][CH2:29][S:28](=[O:31])[CH2:27][CH2:26]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][CH2:14][C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([O:23][CH3:24])[CH:16]=3)[C:6]=2[N:7]=1.[OH:32][CH2:33][CH2:34][NH2:35]>>[CH3:24][O:23][C:17]1[CH:16]=[C:15]([CH:20]=[CH:19][C:18]=1[O:21][CH3:22])[CH2:14][CH2:13][NH:12][C:8]1[C:6]2[N:7]=[C:2]([NH:35][CH2:34][CH2:33][OH:32])[N:3]=[C:4]([N:25]3[CH2:30][CH2:29][S:28](=[O:31])[CH2:27][CH2:26]3)[C:5]=2[N:11]=[CH:10][N:9]=1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 12817047HCID 12817047, compound

Product 1

HCID 13043515HCID 13043515, compound

Procedure

This compound was prepared analogous to Example 2 from 2-chloro-8-(3,4-dimethoxyphenethyl-amino)-4-(1-oxidothiomorpholino)-pyrimido[5,4-d]pyrimidine (melting point: 214°-216° C.) and 2-hydroxyethyl-amine.

Sources & evidence

ORD record
ord-a607f9df36f542ee933d3f6049a6401e
Source dataset
uspto-grants-1984_10
Patent number
US04478833

Reaction notes

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