Benzenepropanoyl chloride → HCID 12582692, compound

HRID 1633040Notes

Reaction equation

HRID 1633040 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:21])[CH2:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:11][C:4]=2[CH:3]=1.C(O)(=O)/C=C\C(O)=O.ClC1[N:36]=[N:35]C2CCNCC=2C=1.C1(CCC(Cl)=O)C=CC=CC=1>C(O)C>[NH:35]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:21])[CH2:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:11][C:4]=2[CH:3]=1)[NH2:36]

Participants

5

Reactant 3

HCID 64801Benzenepropanoyl chlorideHCID 20441606HCID 20441606, compoundHCID 86733381HCID 86733381, compound

Product 1

HCID 12582692HCID 12582692, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The 3-chloro-5,6,7,8-tetrahydro-6-(3-phenylpropionyl)pyrido[4,3-c]pyridazine, required as starting material, may be obtained in a manner analogous to that described in Example 8(g), from 28.6 g of 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and 31.5 g of 3-phenylpropionyl chloride. M.P. 134°-137° from 95% ethanol.

Workup

  1. custommay be obtained in a manner analogous to

Sources & evidence

ORD record
ord-a915e1dbbc7c492d93d642091e4ff6b9
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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