Butyryl chloride → HCID 12582639, compound

HRID 1633052Notes

Reaction equation

HRID 1633052 reaction equation
[C:1]([N:6]1[CH2:16][CH2:15][C:9]2[N:10]=[N:11][C:12](Cl)=[CH:13][C:8]=2[CH2:7]1)(=[O:5])[CH2:2][CH2:3][CH3:4].C(O)(=O)/C=C\C(O)=O.ClC1[N:31]=[N:30]C2CCNCC=2C=1.C(Cl)(=O)CCC>C(#N)C>[C:1]([N:6]1[CH2:16][CH2:15][C:9]2[N:10]=[N:11][C:12]([NH:30][NH2:31])=[CH:13][C:8]=2[CH2:7]1)(=[O:5])[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 8855Butyryl chlorideHCID 20441603HCID 20441603, compoundHCID 86733381HCID 86733381, compound

Product 1

HCID 12582639HCID 12582639, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The 6-butyryl-3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine, required as starting material, may be produced in a manner analogous to that described in Example 8(g), from 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and butyric acid chloride. Reaction time 27 hours. M.P. 130°-133° from acetonitrile.

Workup

  1. custommay be produced in a manner analogous to
  2. customReaction time 27 hours

Sources & evidence

ORD record
ord-e7d921ab31c345568b962c0f4618baea
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

Loading…