Cyclohexanecarbonyl chloride → HCID 12582654, compound

HRID 1633053Notes

Reaction equation

HRID 1633053 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:19])[CH:13]3[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]3)[CH2:11][C:4]=2[CH:3]=1.C(O)(=O)/C=C\C(O)=O.ClC1[N:34]=[N:33]C2CCNCC=2C=1.C1(C(Cl)=O)CCCCC1>C(O)C>[NH:33]([C:2]1[N:7]=[N:6][C:5]2[CH2:8][CH2:9][N:10]([C:12](=[O:19])[CH:13]3[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]3)[CH2:11][C:4]=2[CH:3]=1)[NH2:34]

Participants

5

Reactant 3

HCID 75938Cyclohexanecarbonyl chlorideHCID 20441548HCID 20441548, compoundHCID 86733381HCID 86733381, compound

Product 1

HCID 12582654HCID 12582654, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The 3-chloro-6-hexahydrobenzoyl-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine, required as starting material, may be produced in a manner analogous to that described in Example 8(g), from 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and cyclohexanecarboxylic acid chloride. M.P. 144°-146° (decomp., from absolute ethanol).

Workup

  1. custommay be produced in a manner analogous to

Sources & evidence

ORD record
ord-26af956052d3494f96422fc64ee00649
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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