Pyrido(4,3-c)pyridazine-6(5H)-carboxylic acid, 7,8-dihydro-3-hydrazino-, ethyl ester → HCID 86739705, compound

HRID 1633074Notes

Reaction equation

HRID 1633074 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH2:17][CH2:16][C:9]2[N:10]=[N:11][C:12](NN)=[CH:13][C:8]=2[CH2:7]1)=[O:5])[CH3:2]>CC(C)=O>[CH2:1]([O:3][C:4]([N:6]1[CH2:17][CH:16]([NH:11][N:10]=[C:9]([CH3:16])[CH3:8])[C:9]2[N:10]=[N:11][CH:12]=[CH:13][C:8]=2[CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 1

HCID 217824Pyrido(4,3-c)pyridazine-6(5H)-carboxylic acid, 7,8-dihydro-3-hydrazino-, ethyl ester

Product 1

HCID 86739705HCID 86739705, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A suspension of 23.7 g of 3-hydrazino-5,6,7,8-tetrahydro-6-pyrido[4,3-c]pyridazinecarboxylic acid ethyl ester in 100 cc of acetone is heated at reflux for 4 hours while stirring. The title compound has a M.P. of 171°-174° (decomp., from methanol).

Workup

  1. temperatureis heated
  2. temperatureat reflux for 4 hours

Sources & evidence

ORD record
ord-1b8b38ad4b2e428a8a61682335e9724c
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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