Pyrido(4,3-c)pyridazine-6(5H)-carboxylic acid, 7,8-dihydro-3-hydrazino-, ethyl ester → HCID 70510307, compound

HRID 1633075Notes

Reaction equation

HRID 1633075 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH2:17][CH2:16][C:9]2[N:10]=[N:11][C:12]([NH:14][NH2:15])=[CH:13][C:8]=2[CH2:7]1)=[O:5])[CH3:2]>CC(CC)=O>[CH2:1]([O:3][C:4]([N:6]1[CH2:17][CH2:16][C:9]2[N:10]=[N:11][C:12]([NH:14][N:15]=[CH:7][CH2:8][CH2:9][CH3:16])=[CH:13][C:8]=2[CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 1

HCID 217824Pyrido(4,3-c)pyridazine-6(5H)-carboxylic acid, 7,8-dihydro-3-hydrazino-, ethyl ester

Product 1

HCID 70510307HCID 70510307, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

A suspension of 23.7 g of 3-hydrazino-5,6,7,8-tetrahydro-6-pyrido[4,3-c]pyridazinecarboxylic acid ethyl ester in 100 cc of methylethyl ketone is heated at reflux for 4 hours while stirring. The title compound has a M.P. of 142°-146° (decomp., from methanol).

Workup

  1. temperatureis heated
  2. temperatureat reflux for 4 hours

Sources & evidence

ORD record
ord-d9e346cc0e0046d296df8f320115af98
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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