Cyclohexanone → HCID 20441536, compound

HRID 1633083Notes

Reaction equation

HRID 1633083 reaction equation
[NH:1]([C:3]1[N:8]=[N:7][C:6]2[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:5]=2[CH:4]=1)[NH2:2].[C:15]1(=O)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[C:15]1(=[N:2][NH:1][C:3]2[N:8]=[N:7][C:6]3[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:5]=3[CH:4]=2)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 7967CyclohexanoneHCID 12582745HCID 12582745, compound

Product 1

HCID 20441536HCID 20441536, compound

Procedure

A solution of 10.0 g of 3-hydrazino-5,6,7,8,9,10-hexahydrocycloocta[c]pyridazine in 100 cc of cyclohexanone is boiled at reflux at a bath temperature of 180° for 1 hour and 45 minutes. The mixture is concentrated in a vacuum, whereby the crystalline title compound is obtained and is recrystallized from isopropanol. M.P. 160°-162° (decomp.).

Workup

  1. temperatureat reflux at a bath temperature of 180° for 1 hour
  2. custom45 minutes
  3. concentrationThe mixture is concentrated in a vacuum, whereby the crystalline title compound
  4. customis obtained
  5. customis recrystallized from isopropanol

Sources & evidence

ORD record
ord-e1f7ffcaf34e44468fea793abe395711
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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