Endralazine → HCID 70510851, compound

HRID 1633085Notes

Reaction equation

HRID 1633085 reaction equation
[C:1]([N:9]1[CH2:20][CH2:19][C:12]2[N:13]=[N:14][C:15]([NH:17][NH2:18])=[CH:16][C:11]=2[CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CC(CC)=O>[C:1]([N:9]1[CH2:20][CH2:19][C:12]2[N:13]=[N:14][C:15]([NH:17][N:18]=[CH:1][CH2:2][CH2:3][CH3:4])=[CH:16][C:11]=2[CH2:10]1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 47608Endralazine

Product 1

HCID 70510851HCID 70510851, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

A suspension of 13.5 g of 6-benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine in 100 cc of methylethyl ketone is heated at reflux while stirring for 4 hours. The title compound has a M.P. of 191°-193°, from 95% ethanol.

Workup

  1. temperatureis heated
  2. temperatureat reflux

Sources & evidence

ORD record
ord-3f66c5d1cc5c42b69e29ea5ccb4f2267
Source dataset
uspto-grants-1984_10
Patent number
US04478837

Reaction notes

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