HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15591375, compound → HCID 13362104, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15591375 | HCID 15591375 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | HCID 13362104 | HCID 13362104 | — |
Reaction Steps
A solution of 1.70 g of 1-(5-carboxypentyl)-5-methoxy-3-methyl-2-(3-pyridyl)indole in 85 ml of 48% hydrobromic acid is heated under reflux for 0.5 hour. The reaction mixture is evaporated to dryness, diluted with water and adjusted to pH 6 with dilute sodium hydroxide. The precipitate is collected and recrystallized from acetone-ether to yield 1-(5-carboxypentyl)5-hydroxy-3-methyl-2-(3-pyridyl)indole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04478842 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-441be0b3e134414698d438dfc541fbde |
| Source note | uspto-grants-1984_10 |