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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633127Generated: November 1, 2026

HCID 20441659, compound → HCID 70490518, compound

https://huagongshe.com/reaction/1633127

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 20441659HCID 20441659—
SolventHydrochloric AcidHCID 313—
ProductHCID 70490518HCID 70490518—

Reaction Steps

Heating a suspension of 7.5 g of ethyl 3-methyl-2-(3-pyridyl)indole-5-propionate hydrochloride in 450 ml of 2N HCl at reflux temperature for 2 hours, cooling and collecting the resulting solid gives 3-methyl-2-(3-pyridyl)-indole-5-propionic acid hydrochloride, m.p. 290°. Similar hydrolysis of ethyl 3-methyl-2-(4-pyridyl)indole-5-propionate yields 3-methyl-2-(4-pyridyl)indole-5-propionic acid hydrochloride, melting above 305°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04478842
Source datasetuspto-grants-1984_10
ORD IDord-3ca3e8dfef84425e9aed95134902ed73
Source noteuspto-grants-1984_10