HuagongsheHuagongshe Chemistry Print Report · For research reference only
Amyl Acetate → Amyl 3-Hydroxy-3-methyl-3-(4-pyridyl)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Amyl Acetate | HCID 12348 | — |
| Reactant | 4-Acetylpyridine | HCID 14282 | — |
| Product | Amyl 3-Hydroxy-3-methyl-3-(4-pyridyl)propionate | HCID 20441861 | 74% |
Reaction Steps
The reaction of 4-acetylpyridine (24.2 grams, 0.2 mole) with the enolate of amyl acetate (26.0 grams, 0.2 mole) is carried out as described in Example I. Distillation yields 37.2 grams (74%) of the pure product b.p. 102°-105° C. (air bath temperature) at 0.05 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04479003 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-db9da96c6de64a07a5f6c7d03bb36684 |
| Source note | uspto-grants-1984_10 |