Water → HCID 20439634, compound

HRID 1633189Notes

Reaction equation

HRID 1633189 reaction equation
[CH2:1]([NH2:5])[CH:2]([CH3:4])[CH3:3].Cl[C:7]1[C:12]([Cl:13])=[C:11]([Cl:14])[CH:10]=[CH:9][C:8]=1[N+:15]([O-:17])=[O:16].O>C1(C)C=CC=CC=1>[Cl:13][C:12]1[C:11]([Cl:14])=[CH:10][CH:9]=[C:8]([N+:15]([O-:17])=[O:16])[C:7]=1[NH:5][CH2:1][CH:2]([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 962WaterHCID 6558Isobutylamine2×HCID 286972,3,4-Trichloronitrobenzene

Product 1

HCID 20439634HCID 20439634, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Conditions

Temperature
60 °C

Procedure

Forty-eight grams of isobutylamine and 75.5 gm of 2,3,4-trichloronitrobenzene were dissolved in 200 ml of toluene and kept at room temperature for 3 days. The mixture was then treated with a further 5 gm of isobutylamine and heated to 60° C. for 4 hours. The toluene solution was shaken with water, dried, and evaporated. The yield was 86 gm of 2,3-dichloro-6-nitro-N-isobutylaniline (98% of theory), which was obtained as a brownish oil.

Workup

  1. customdried
  2. customevaporated

Sources & evidence

ORD record
ord-7547a8ed5c50492087d4ea573c45b44c
Source dataset
uspto-grants-1984_10
Patent number
USRE031717

Reaction notes

Loading…