2-Amino-4-methoxy-6-methyl-1,3,5-triazine → HCID 13729477, compound

HRID 1633197Notes

Reaction equation

HRID 1633197 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[S:12]([N:15]=[C:16]=[O:17])(=[O:14])=[O:13].[NH2:18][C:19]1[N:24]=[C:23]([O:25][CH3:26])[N:22]=[C:21]([CH3:27])[N:20]=1>O1CCOCC1>[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[S:12]([NH:15][C:16]([NH:18][C:19]1[N:24]=[C:23]([O:25][CH3:26])[N:22]=[C:21]([CH3:27])[N:20]=1)=[O:17])(=[O:14])=[O:13]

Participants

4

Reactant 2

HCID 154662-Amino-4-methoxy-6-methyl-1,3,5-triazineHCID 204396542-(2-Methoxyethoxy)benzene-1-sulfonyl isocyanate

Product 1

HCID 13729477HCID 13729477, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

9.0 g of 2-methoxyethoxy-phenylsulfonyl isocyanate and 4.9 g of 2-amino-4-methoxy-6-methyl-1,3,5-triazine are refluxed in 60 ml of absolute dioxane for 3 hours. The mixture is treated with activated carbon, filtrated and evaporated to 1/5 of the original volume. After addition of ether 13.0 g of N-(2-methoxyethoxy-phenylsulfonyl)-N'-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-urea crystallise therefrom, m.p. 134°-138° C.

Workup

  1. additionThe mixture is treated with activated carbon
  2. filtrationfiltrated
  3. customevaporated to 1/5 of the original volume
  4. additionAfter addition of ether 13.0 g of N-(2-methoxyethoxy-phenylsulfonyl)-N'-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-urea
  5. customcrystallise

Sources & evidence

ORD record
ord-9afeb95228e34bb2993db211535b7a89
Source dataset
uspto-grants-1984_10
Patent number
US04479821

Reaction notes

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