3,4,5-Trimethoxybenzeneboronic acid → Adamantan-1-yl-[2-(3,4,5-trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone

HRID 163321Notes

Reaction equation

HRID 163321 reaction equation
[C:1]12([C:11](=[O:12])[c:13]3[cH:14][nH:15][c:16]4[n:17][cH:18][c:19]([Br:22])[n:20][c:21]34)[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2.[CH3:23][O:24][c:25]1[cH:26][c:27]([B:35]([OH:36])[OH:37])[cH:28][c:29]([O:33][CH3:34])[c:30]1[O:31][CH3:32]>>[C:1]12([C:11](=[O:12])[c:13]3[cH:14][nH:15][c:16]4[n:17][cH:18][c:19](-[c:27]5[cH:26][c:25]([O:24][CH3:23])[c:30]([O:31][CH3:32])[c:29]([O:33][CH3:34])[cH:28]5)[n:20][c:21]34)[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2

Participants

3

Reactant 2

HCID 27343903,4,5-Trimethoxybenzeneboronic acidHCID 44182410Adamantan-1-yl-(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-methanone

Product 1

HCID 59540589Adamantan-1-yl-[2-(3,4,5-trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone

Sources & evidence

ORD record
ord-2d3bf6d2bcec4e7e99be03eee6a80cc4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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