Formic Acid → HCID 20440420, compound

HRID 1633260Notes

Reaction equation

HRID 1633260 reaction equation
[ClH:1].Cl.Cl.[NH2:4][C:5]1[C:6]([NH:28][CH3:29])=[C:7]([O:11][CH2:12][CH:13]([OH:27])[CH2:14][NH:15][CH2:16][CH2:17][NH:18][C:19]2[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][C:20]=2[CH3:26])[CH:8]=[CH:9][CH:10]=1.[CH:30](O)=O>>[ClH:1].[ClH:1].[CH3:29][N:28]1[C:6]2[C:7]([O:11][CH2:12][CH:13]([OH:27])[CH2:14][NH:15][CH2:16][CH2:17][NH:18][C:19]3[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][C:20]=3[CH3:26])=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[CH:30]1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 20440407HCID 20440407, compound

Product 1

HCID 20440420HCID 20440420, compound

Procedure

In a manner analogous to the preceding Example, by reacting 3-amino-2-methylamino-1-(2-hydroxy-3-[2-(2,6-dimethylphenylamino)-ethylamino]-propoxy)-benzene trihydrochloride with formic acid, there are obtained 2.1 g. (14% of theory) of the desired compound; m.p. 94°-96° C. (after recrystallization from ethanol/diethyl ether).

Workup

  1. customare obtained 2.1 g

Sources & evidence

ORD record
ord-f51cf821725243b7b062e86cfda7a27e
Source dataset
uspto-grants-1984_10
Patent number
US04479962

Reaction notes

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