Pentanedioic acid, 2-(1-methylethyl)- → 3-(Propan-2-yl)oxane-2,6-dione

HRID 1633267Notes

Reaction equation

HRID 1633267 reaction equation
[CH:1]([CH:4]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[C:5]([OH:7])=O)([CH3:3])[CH3:2]>C(Cl)(=O)C>[CH:1]([CH:4]1[CH2:8][CH2:9][C:10](=[O:11])[O:12][C:5]1=[O:7])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 3511510Pentanedioic acid, 2-(1-methylethyl)-

Product 1

HCID 142948783-(Propan-2-yl)oxane-2,6-dione

Reagents, catalysts & solvents 1

HCID 6367Acetyl chlorideSolvent

Procedure

The starting material is prepared as follows: A solution of 14.0 g of 2-isopropylglutaric acid in 80 ml of acetyl chloride is stirred at 50° for 2 hours and then evaporated to give 2-isopropylglutaric anhydride with NMR peaks at 0.98, 1.89, 2.43 and 2.85 ppm.

Workup

  1. customThe starting material is prepared
  2. customevaporated

Sources & evidence

ORD record
ord-c63c11b1dd0047b6a1145bb01e44d904
Source dataset
uspto-grants-1984_10
Patent number
US04479963

Reaction notes

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