HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Benzyloxycarbonyl-beta-alanine → 1-(6-Benzoylamino-9H-purin-9-yl)-3-(N-benzyloxycarbonyl-beta-alanylamino)-1,3-dideoxy-beta-D-ribofuranuronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Benzyloxycarbonyl-beta-alanine | HCID 75313 | — |
| Reactant | 3-amino-1-(6-benzoylamino-9H-purin-9-yl)-1,3-dideoxy-beta-D-ribofuranuronic acid | HCID 53854008 | — |
| Product | 1-(6-Benzoylamino-9H-purin-9-yl)-3-(N-benzyloxycarbonyl-beta-alanylamino)-1,3-dideoxy-beta-D-ribofuranuronic acid | HCID 70465439 | 100.2% |
Reaction Steps
1-(6-Benzoylamino-9H-purin-9-yl)-3-(N-benzyloxycarbonyl-β-alanylamino)-1,3-dideoxy-β-D-ribofuranuronic acid (590 mg) was prepared by reacting 1-(6-benzoylamino-9H-purin-9-yl)-1,3-dideoxy-3-amino-β-D-ribofuranuronic acid (384 mg) prepared in Example 1 with N-hydroxysuccinimide ester of N-benzyloxycarbonyl-β-alanine (450 mg) according to a similar manner to that of Example 5, mp. 136°-141° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04479942 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-eba6cfc3d6d74e4bbd9b147d3991a9f7 |
| Source note | uspto-grants-1984_10 |