N-Formyl-L-phenylalanine → (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3-[[(2S)-2-formamido-3-phenyl-propanoyl]amino]-4-hydroxy-tetrahydrofuran-2-carboxylic acid

Participants

Reaction Steps

1-(6-Amino-9H-purin-9-yl)-1,3-dideoxy-3-(N-formyl-L-phenylalanylamino)-β-D-ribofuranuronic acid (58 mg) was prepared by reacting 1-(6-amino-9H-purin-9-yl)-1,3-dideoxy-3-amino-β-D-ribofuranuronic acid monohydrate (140 mg) prepared in Example 99 with N-hydroxysuccinimide ester of N-formyl-L-phenylalanine (130 mg) according to a similar manner to that of Example 5, mp. 169°-181° C. (dec.).

Provenance & Evidence