HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-Mandelic acid → HCID 131713953, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-Mandelic acid | HCID 11914 | — |
| Reactant | 5-Phenyl-1,3-dioxolane-2,4-dione | HCID 15602392 | — |
| Reactant | 3-amino-1-(6-benzoylamino-9H-purin-9-yl)-1,3-dideoxy-beta-D-ribofuranuronic acid | HCID 53854008 | — |
| Product | HCID 131713953 | HCID 131713953 | 74.1% |
Reaction Steps
1-(6-Benzoylamino-9H-purin-9-yl)-3-D-mandelylamino-1,3-dideoxy-β-D-ribofuranuronic acid (300 mg) was prepared by reacting 1-(6-benzoylamino-9H-purin-9-yl)-1,3-dideoxy-3-amino-β-D-ribofuranuronic acid (300 mg) prepared in Example 1 with 2,4-dioxo-5-phenyl-1,3-dioxolane (253 mg), prepared from D-mandelic acid, according to a similar manner to that of Example 5, mp. 223°-227° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04479942 |
| Source dataset | uspto-grants-1984_10 |
| ORD ID | ord-dd6f5b9bb2414c3e9ca29171143bd199 |
| Source note | uspto-grants-1984_10 |