Butylamine → 1-(6-Amino-9H-purin-9-yl)-3-[N-tert-butoxycarbonyl-beta-(4-fluorophenyl)-D,L-alanylamino]-1,3-dideoxy-beta-D-ribofuranuronic acid

Participants

Reaction Steps

1-(6-Amino-9H-purin-9-yl)-3-[N-tert-butoxycarbonyl-β-(4-fluorophenyl)-D,L-alanylamino]-1,3-dideoxy-β-D-ribofuranuronic acid (400 mg) was prepared by reacting 1-(6-benzoylamino-9H-purin-9yl)-3-[N-tert-butoxycarbonyl-β-(4-fluorophenyl)-D,L-alanylamino]-1,3-dideoxy-β-D-ribofuranuronic acid (543 mg) prepared in Example 9 with n-butylamine (5.0 ml) according to a similar manner to that of Example 23, mp. 149°-154° C. (dec.).

Provenance & Evidence