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HRID1633295

反应详情

EQUATION

反应方程式

HRID 1633295 的结构方程式

REACTANTS

反应物

2
反应SMILES：CCCCN
HCID8007

Butylamine

C4H11N

反应SMILES：C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@@H](O)[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@@H]1C(=O)O
HCID70465603

未命名化合物

PRODUCTS

产物

1
反应SMILES：C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H]1[C@@H](O)[C@H](n2cnc3c(N)ncnc32)O[C@@H]1C(=O)O
HCID70465258

未命名化合物

收率 82.4%

PROCEDURE

实验过程

1-(6-Amino-9H-purin-9-yl)-3-(N-benzyloxycarbonyl-L-alanylamino)-1,3-dideoxy-β-D-ribofuranuronic acid (190 mg) was prepared by reacting 1-(6-benzoylamino-9H-purin-9-yl)-3-(N-benzyloxycarbonyl-L-alanylamino)-1,3-dideoxy-β-D-ribofuranuronic acid (280 mg) prepared in Example 13 with n-butylamine (1.5 ml) according to a similar manner to that of Example 23, mp. 151°-156° C. (dec.).