Butylamine → HCID 476107, compound

HRID 1633298Notes

Reaction equation

C([NH:9][C:10]1[N:18]=[CH:17][N:16]=[C:15]2[C:11]=1[N:12]=[CH:13][N:14]2[C@@H:19]1[O:24][C@H:23]([C:25]([OH:27])=[O:26])[C@@H:22]([NH:28][C:29](=[O:38])[C@@H:30]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[OH:31])[C@H:20]1[OH:21])(=O)C1C=CC=CC=1.C(N)CCC>>[NH2:9][C:10]1[N:18]=[CH:17][N:16]=[C:15]2[C:11]=1[N:12]=[CH:13][N:14]2[C@@H:19]1[O:24][C@H:23]([C:25]([OH:27])=[O:26])[C@@H:22]([NH:28][C:29](=[O:38])[C@@H:30]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[OH:31])[C@H:20]1[OH:21]

Participants

Reactant 2

HCID 8007Butylamine

HCID 131713953HCID 131713953, compound

Product 1

HCID 476107HCID 476107, compoundYield 11.8%

Procedure

1-(6-Amino-9H-purin-9-yl)-3-D-mandelylamino-1,3-dideoxy-β-D-ribofuranuronic acid (35 mg) was prepared by reacting 1-(6-benzoylamino-9H-purin-9-yl)-3-D-mandelylamino-1,3-dideoxy-β-D-ribofuranuronic acid (370 mg) prepared in Example 22 with n-butylamine (3ml) according to a similar manner to that of Example 23.

Sources & evidence

ORD record: ord-8bed647f69bf438f8aef507977e7e37c
Source dataset: uspto-grants-1984_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04479942

Reaction notes

Loading…