2-Trifluoromethylbenzenesulphonyl chloride → HCID 9937258, compound

HRID 1633462Notes

Reaction equation

HRID 1633462 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH:11][CH:12]([CH3:36])[C:13]([NH:15][CH:16]1[C:22](=[O:23])[N:21]([CH3:24])[C:20]2[CH:25]=[CH:26][CH:27]=[CH:28][C:19]=2[C:18]([C:29]2[CH:34]=[CH:33][C:32](F)=[CH:31][CH:30]=2)=[N:17]1)=[O:14])(=[O:10])=[O:9].[F:37][C:38]([F:50])([F:49])C1C=CC=CC=1S(Cl)(=O)=O>>[CH3:24][N:21]1[C:20]2[CH:25]=[CH:26][CH:27]=[CH:28][C:19]=2[C:18]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[N:17][CH:16]([NH:15][C:13](=[O:14])[CH:12]([NH:11][S:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[C:38]([F:50])([F:49])[F:37])(=[O:10])=[O:9])[CH3:36])[C:22]1=[O:23]

Participants

3

Reactant 2

HCID 1366162-Trifluoromethylbenzenesulphonyl chlorideHCID 9892621HCID 9892621, compound

Product 1

HCID 9937258HCID 9937258, compoundYield 68%

Procedure

The compound of Example 53 was synthesized in a procedure analogous to the synthesis of the compound of Example 52 using 2-trifluoromethyl benzene sulfonyl chloride in 68% yield. MS (ESI) M+H=545.2

Sources & evidence

ORD record
ord-cda7a9770a31451fbfcbe67c3aff8c8b
Source dataset
uspto-grants-2003_01
Patent number
US06503901B1

Reaction notes

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