Methanol → HCID 178486607, compound

Participants

Reaction Conditions

Reaction Steps

7.6 g (0.025 mol) of 5,7-dibromoisatin, 6.15 g (0.025 mol) of 5,7-di-tert-butyl-3H-benzofuran-2-one and 0.5 g of p-toluenesulfonic acid are boiled in 25 ml of acetic acid under nitrogen for 21 hours. 40 ml of methanol are then added and the suspension obtained is cooled to 5° C. The solid then obtained is filtered off and the filter residue is washed with methanol and dried at 60° C. The yield is 10.7 g (80% of theory). Melting point: 303-314° C. C: calculated/found 49.73/49.46; H: calculated/found 3.38/3.45; N: calculated/found 2.76/2.73

Provenance & Evidence