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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633623Generated: November 1, 2026

Methylamine → {4-[1-(4-Fluoro-phenyl)-1H-indol-5-yloxy]-butyl}-methylamine

https://huagongshe.com/reaction/1633623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant5-(4-Bromo-butoxy)-1-(4-fluoro-phenyl)-1H-indoleHCID 18679427—
Product{4-[1-(4-Fluoro-phenyl)-1H-indol-5-yloxy]-butyl}-methylamineHCID 18679487—

Reaction Steps

In analogy to example 3.3, 5-(4-Bromo-butoxy)-1-(4-fluoro-phenyl)-1H-indole and methylamine were converted to yield {4-[1-(4-Fluoro-phenyl)-1H-indol-5-yloxy]-butyl}-methyl-amine as colorless crystalline, mp 49-50° C., MS: 313 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06503907B2
Source datasetuspto-grants-2003_01
ORD IDord-7f84f267f452416b9d50fe0b3ab519f0
Source noteuspto-grants-2003_01