2-Fluorobiphenyl → HCID 18679501, compound

HRID 1633632Notes

Reaction equation

HRID 1633632 reaction equation
[CH2:1]([N:3]([CH2:18][CH3:19])[CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][CH:13]=[CH:12]2)[CH3:2].F[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[C:22]1([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=1[N:14]1[C:15]2[C:11](=[CH:10][C:9]([O:8][CH2:7][CH2:6][CH2:5][CH2:4][N:3]([CH2:1][CH3:2])[CH2:18][CH3:19])=[CH:17][CH:16]=2)[CH:12]=[CH:13]1

Participants

3

Reactant 2

HCID 675792-FluorobiphenylHCID 18679455Diethyl-[4-(1H-indol-5-yloxy)-butyl]-amine

Product 1

HCID 18679501HCID 18679501, compound

Procedure

In analogy to example 4.6, Diethyl-[4-(1H-indol-5-yloxy)-butyl]-amine and 2-fluorobiphenyl were converted to yield [4-(1-Biphenyl-2-yl-1H-indol-5-yloxy)-butyl]-diethyl-amine as light yellow oil, MS: 412 (M).

Sources & evidence

ORD record
ord-6e4d9bb53e90459aa12a96c02eb88d4a
Source dataset
uspto-grants-2003_01
Patent number
US06503907B2

Reaction notes

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