HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18679567, compound → HCID 18679499, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18679567 | HCID 18679567 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | HCID 18679499 | HCID 18679499 | 62.1% |
Reaction Steps
3.8 g (10 mmol) 5-Benzyloxy-1-(4-bromo-phenyl)-1H-indole in 30 ml EtOAc and 10 ml EtOH were hydrogenated in the presence of 5% Pd/C. Column chromatography on silica gel in hexane/EtOAc 5:1 yielded 1.3 g (62%) 1-Phenyl-1H-indol-5-ol as colorless viscous oil, MS: 209 (M).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06503907B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-5e67c18e47c1468584f30138cf4a261a |
| Source note | uspto-grants-2003_01 |