1,4-Dibromobutane → HCID 18679514, compound

HRID 1633658Notes

Reaction equation

HRID 1633658 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:16]3[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=3)[CH:10]=[CH:9]2)=[CH:4][CH:3]=1.[Br:18][CH2:19][CH2:20][CH2:21][CH2:22]Br>>[Br:18][CH2:19][CH2:20][CH2:21][CH2:22][O:17][C:13]1[CH:12]=[C:11]2[C:16](=[CH:15][CH:14]=1)[N:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=1)[CH:9]=[CH:10]2

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 18679504HCID 18679504, compound

Product 1

HCID 18679514HCID 18679514, compound

Procedure

In analogy to example 3.1, 1-(4-Bromo-phenyl)-1H-indol-5-ol and 1,4-dibrombutane were converted to yield 5-(4-Bromo-butoxy)-1-(4-bromo-phenyl)-1H-indole as light yellow solid, mp 80-81° C., MS: 421 (M, 2Br).

Sources & evidence

ORD record
ord-13d72aecbade4d4884a6dc32df52346d
Source dataset
uspto-grants-2003_01
Patent number
US06503907B2

Reaction notes

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